Paternal obesity can be inherited for several generations

The sperm of obese fathers may increase the risk of hereditary obesity in their children and grandchildren, a new study from the University of Adelaide has concluded.

In a lab study, researchers at the Robinson University Institute found that molecular signals in fathers’ sperm can lead to obesity and diabetes and similar symptoms in two generations of their offspring, even with healthy diets.

“The father’s diet alters the molecular composition of sperm in obese fathers, making changes to their sperm. These microRNA molecules can program the embryo for obesity or a metabolic disease later in life,” says lead author Dr. Tod . Fallston , who is a fellow at the University’s Robinson Institute.

The study also showed an extension of the disease to the second generation of offspring, which also showed signs of similar metabolic disorders, including obesity, although this was not as severe as in the first generation.

Even if the father’s obesity does not show any signs of diabetes, metabolic diseases such as diabetes mellitus are now seen in two generations of their offspring.

The fact that a mother’s health before, during and after pregnancy can affect the health of her child was already known, but the health of the father during this period was often overlooked. Focusing on the health of the mother is extremely important, but the health of the father is also important for conception. It is possible that the father’s extra focus on diet and exercise could have a positive impact on the future of his children and grandchildren.

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